Up to 40% of dementia cases could be thwarted by modifying 12 key risk factors, according to a report by the Lancet Commission. Many of these factors can be tackled late in life, the authors say.
Adults who maintain high cognitive performance into late age appear to defy the brain’s normal aging processes and escape neurodegeneration, say researchers.
Apathy is a distinct sign of looming dementia in individuals at risk, say researchers. Monitoring patients for this symptom could catch the problem early on, they argue.
Training and support leads to discontinuation of antipsychotic meds in residents who do not have a diagnosis of psychosis or mental health issues, researchers have found. Notably, behavioral symptoms did not worsen during the multi-center study.
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Bupropion had no effect in the largest trial yet to study apathy treatment in Alzheimer’s, say investigators.
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Higher cardiovascular risk is tied to cognitive decline and neurodegeneration, a study spanning more than two decades has found.
Study participants with both conditions had “particularly poor functionality” with relative scores nearly 50% lower for all activity limitations evaluated.
When social distancing measures are eased, adults with dementia may need greater protections due to their risk profile, researchers say.
