Study to examine severe side effects tied to Alzheimer’s drug combo
Millions of Medicare records will be used to analyze how two drug classes commonly used to treat Alzheimer’s may lead to a ‘prescription cascade’ when taken together.
Antipsychotics
Antipsychotic misuse citations down 22%; drugs given 10 times too often: House report
Skilled nursing providers have received far fewer citations for antipsychotic misuse under the Trump administration, according to authors of a report released Monday by Democrats on the House Ways and Means Committee.
Collaborative model helps reduce antipsychotic drug use
Training and support leads to discontinuation of antipsychotic meds in residents who do not have a diagnosis of psychosis or mental health issues, researchers have found. Notably, behavioral symptoms did not worsen during the multi-center study.
Clinical Briefs for Monday, January 27
Aging breast cancer survivors suffer greater decline in physical function … Living near major roads linked to risk of dementia, Parkinson’s, Alzheimer’s and MS … Black nursing home residents don’t have higher rates of inappropriate antipsychotic use … Improving nursing home-to-ER transitions: an analysis by ER docs
New antipsychotic improves symptoms minus side effects in trial
Antipsychotic drug lumateperone improves schizophrenia symptoms without side effects such as weight gain and metabolic disturbance.
Brain injury risk spikes when Alzheimer’s patients are treated with antipsychotics
Antipsychotics are associated with greater odds of head injury and traumatic brain injury, according to a new Finnish study.
Clinical Briefs for Wednesday, January 8
Antibiograms cannot be used interchangeably between acute care and nursing home affiliates … Antipsychotics raise risk of heart attack, death in hospital study … Lifelong female exercisers benefit from better muscle function … New guidelines available for treating men with age-related low testosterone
Memory care cuts antipsychotic med use in more than 50% of residents
Person-centered memory care led to a significant reduction in the use of off-label antipsychotic medications in a large long-term care study.
Seniors with Alzheimer’s who take antipsychotics hospitalized more frequently
Seniors with Alzheimer’s disease who are prescribed antipsychotics spend 53% more days hospitalized than those not taking antipsychotics.
Clinical Briefs for Thursday, September 5
Immersive reminiscence therapy a “bright spot” in field of dementia therapy … Antipsychotics, haloperidol, show little benefit for delirium … Modifiable dementia risk factors illuminated in new journal supplement … Cancer incidence is rising in wealthy countries
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