FDA advisers object to Alzheimer’s drug aducanumab ahead of final decision
The experimental Alzheimer’s drug aducanumab is not ready for federal approval in June, advisers to the Food and Drug Administration say in a new JAMA editorial.
Alzheimer’s Disease
Alzheimer’s origin story is about metabolism and lifestyle, scientists contend
Alzheimer’s Disease is increasingly being referred to as insulin resistance of the brain, or Type 3 diabetes, a research team says.
Active lifestyle may slow cognitive decline in people with Parkinson’s and dementia gene: study
Greater physical activity at the study’s start appeared to lessen gene-related cognitive decline two years later, the authors report.
Clinical briefs for Monday, March 29
Thirty-day COVID mortality declines in nationwide elder veterans study … Women accumulate Alzheimer’s tau protein in the brain faster than men, research shows … Nearly all healthcare workers have a strong immune response to one Pfizer vaccine dose in new study … GSK seeks emergency use approval for its antibody drug after trial success
Place-of-death disparities for residents with dementia ‘extremely troubling,’ scientists say
End-of-life hospitalization risk among Black residents with severe cognitive impairment is persistently elevated both within and between facilities, a study of long-stay residents shows.
Clinical briefs for Wednesday, March 10
AHCA / NCAL’s #GetVaccinated.us website is up and running … ‘Fear visuals’ may be keeping needle-phobic from getting vaccinated … Psychiatric diagnoses tied to lower age of Alzheimer’s onset … New lung cancer screening guidelines expand access; critics say it’s not enough
People with dementia receive fewer palliative referrals than those with cancer: study
A large study from Canada has found disparities in palliative care referral between people with dementia or organ failure and people with cancer.
Anxiety, depression tied to earlier Alzheimer’s symptom onset
People with anxiety or depression and Alzheimer’s may show dementia symptoms two to three years earlier than their peers without these diagnoses, researchers say.
Clinical briefs for Thursday, Feb. 25
Dementia care report should be ‘catalyst for change,’ committee says … Pain perception may be early disease marker in Alzheimer’s gene carriers … Nursing home first-dose vaccination data released for federal Pharmacy Partnership for Long-Term Care Program … HHS to stop allocating antibody drugs as supplies increase … New U.S. COVID-19 vaccine index contains county-level insight
Drug that targets Alzheimer’s inflammation approved for trial by FDA
An experimental drug meant to treat the “type 3 diabetes” that some scientists believe triggers Alzheimer’s has been approved for a late-stage clinical trial.
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