Nearly half of Alzheimer’s cases are mild, supporting a focus on early intervention
The great prevalence of mild disease underscores the need for interventions that may slow decline or prevent progression in dementia, researchers contend.
The great prevalence of mild disease underscores the need for interventions that may slow decline or prevent progression in dementia, researchers contend.
If approved by the FDA, aducanumab would be the first-ever drug marketed to slow progression of the brain-wasting disease, according to its developer. But an advisory committee was unconvinced of the drug’s efficacy, voting 8 to 1 against recommending approval.
Documents released on Wednesday show that the agency’s staff members already are enthusiastic about the drug’s prospects. If approved, aducanumab could be the first drug on the market to slow Alzheimer’s progression.
Millions of Medicare records will be used to analyze how two drug classes commonly used to treat Alzheimer’s may lead to a ‘prescription cascade’ when taken together.
The experimental blood test rivals the accuracy of standard diagnostic methods and may soon prove to be a cost-effective, accessible tool in the clinical setting, according to some in the scientific community.
The discovery of new biomarkers — along with a focus on repurposed drugs — are optimistic signs for Alzheimer’s research, according to a five-year analysis.
Treatment with aducanumab reduced declines in memory, language, and activities of daily living performance, the drugmaker says.
Failed Alzheimer’s drugs could be repurposed to target an enzyme that may lead to heart attack and stroke, say investigators.
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After a bit of a bumpy ride in 2019, Biogen’s injectable treatment for early Alzheimer’s is set for a late-stage clinical trial.