Researchers have unlocked a promising new strategy for slowing the progression of Alzheimer’s disease. The successful approach: Decrease brain inflammation before the onset of memory problems and cognitive impairment.
“Starting an intervention at the earliest stage of the disease, when cellular and molecular alterations have already been triggered but major damage to the brain has not yet occurred, could offer a way to reduce the number of people who go on to develop full Alzheimer’s dementia,” said research team leader Caterina Scuderi, Ph.D., assistant professor of pharmacology and toxicology from Sapienza, University of Rome.
The researchers designed an animal study to gain a deeper understanding of neuroinflammation’s role in Alzheimer’s disease prior to symptoms.
“Our results help demonstrate that neuroinflammation in Alzheimer’s disease is an extremely complex phenomenon that can change over the disease’s progression and varies based on factors such as affected brain area,” Scuderi added.
The research team’s abstract appears in this month’s issue of The FASEB Journal.
