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Antipsychotic drugs are essentially useless when it comes to treating Alzheimer’s disease, according to a newly released study from Britain.

The report, published in the current issue of Public Library of Science Medicine, assessed the effectiveness of the drugs on 165 Alzheimer’s patients over the course of one full year. Half the patient group continued their prescribed course of antipsychotics, while the other half received a placebo.

After a review of each patient’s mental and physical capacities at the six-month mark, researchers discovered that there was no significant difference between the two groups. Another review after one year revealed much the same results, though study authors noted that some patients could benefit, albeit slightly, from continued use of antipsychotics.