Antidepressant trial news not treated evenhandedly

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When it comes to antidepressant drug trial reporting, makers literally have been accentuating the positive, according to a new analysis. 

The study reviewed 74 antidepressant trials involving 12 drugs between 1987 and 2004. Researchers found that 94% of positive studies - studies that supported the effectiveness of antidepressants such as Prozac and Zoloft - were published, compared with only 14% of less flattering reports.

Selective reporting of favorable studies ultimately may lead to disappointment for patients, said Dr. Erick H. Turner, a psychiatrist and former Food & Drug Administration reviewer. The study was a joint effort between researchers at the Oregon Health and Sciences University, Kent State University and the University of California, Riverside.