New delivery method for pressure wounds and diabetic foot ulcers improves healing

Share this article:

Researchers have developed a new growth factor delivery system that heals wounds such as pressure sores and diabetic foot ulcers faster than previous treatments.

The scientists found that fabricating nanospheres containing keratinocyte growth factor—the protein that promotes healing—improved healing of deep skin wounds in diabetic laboratory mice when the compounds were suspended in fibrin gel. The researchers, from Massachusetts General Hospital, were pleased that one dose of the growth factor resulted in new tissue regeneration within two weeks.

"Previous reports have suggested that KGF can help heal chronic wounds,” said the paper's lead researcher, Piyush Koria. He added that in other studies, the growth factor was administered to the surface of the wound, limiting its ability to penetrate more deeply into it.

“Using large quantities of growth factor would make this therapy extremely expensive. Our work circumvents these limitations by more efficiently delivering KFG throughout the wound to stimulate tissue regeneration," he said. The research was published in the Jan. 18 issue of Proceedings of the National Academy of Sciences.
Share this article:

More in News

Bulk of Medicaid to be managed care in two years: Avalere

Bulk of Medicaid to be managed care in ...

More than three-quarters of Medicaid beneficiaries will be enrolled in a managed care plan as of 2016, according to an Avalere Health analysis released Thursday. The numbers reveal that managed ...

Nursing home asked for employee's personal information too often, jury rules

The human resources department of a Maine nursing home did not properly protect a former employee's personal identification information, a jury recently ruled.

Test could confirm sepsis within an hour

Nursing home residents might benefit from a new way of diagnosing and treating sepsis made possible by discoveries out of the University of British Columbia.