Mechanical stress can influence healing

Share this article:
Mechanical forces affect the growth and remodeling of blood vessels during tissue regeneration and wound healing, a new study concludes. Such forces diminish or enhance the vascularization process and tissue regeneration depending on when they are applied during the healing process.

Investigators from the Georgia Institute of Technology found that applying mechanical forces to an injury site immediately after healing began disrupted vascular growth into the site and prevented bone healing. However, applying mechanical forces later in the healing process enhanced functional bone regeneration.

The study's findings could influence treatment of tissue injuries and rehabilitation recommendations, researchers claimed.

“The findings suggest applying mechanical stresses to the wound later on can significantly improve healing through a process called adaptive remodeling,” said Robert Guldberg, Ph.D., a professor at the university.

Guldberg and his team used healing of a bone defect in rats for their study. 

Full findings appear in the Proceedings of the National Academy of Sciences.
Share this article:

More in News

Skilled nursing facility trends contribute to improved Medicare outlook, Congressional report says

The Medicare trust fund is on track to remain solvent until 2030, trustees of the program stated in a Congressional report released Monday. This improved outlook is due in part to revised expectations about the case mix in skilled nursing facilities.

House bill would define, promote coordinated long-term care services

A bill introduced in the House of Representatives would target improved care coordination for seniors, also adding it under the Older Americans Act.

Seize the day: Tech Awards deadline is tomorrow

Seize the day: Tech Awards deadline is tomorrow

The final countdown has begun: Long-term care providers have less than 48 hours to enter the third annual McKnight's Excellence in Technology Awards. Submissions will be accepted through July 30.