Latest big hope against Alzheimer's falls flat in clinical trials

Share this article:
A promising potential treatment for Alzheimer's disease has failed to produce results in the late stages of a clinical trial, according to recent reports.

The drug, Dimebon, had shown immense promise for halting cognitive decline during early testing, according to a report in the New York Times. Originally marketed as an antihistamine in Russia during the 1980s, Dimebon was being developed as an Alzheimer's treatment by San Francisco-based Medivation and global drug giant Pfizer. The results of the first late-stage clinical trial, however, showed that the once-promising drug had virtually no effect after six months of treating mild to moderate Alzheimer's compared with a placebo, the Times reported.

Tests will continue to determine whether Dimebon is effective when coupled with other medications, and the drug is still being tested as a potential treatment for Huntington's disease, the newspaper said. The price of Medivation stock fell by nearly two-thirds to $13.10 Wednesday.


Share this article:

More in News

Long-term care continues to lead in deal volume and value: PwC report

Long-term care continues to lead in deal volume ...

Long-term care bucked healthcare industry trends with strong merger and acquisition activity in the second quarter of 2014, according to newly released data from professional services firm PricewaterhouseCoopers.

Empowering nurse practitioners could reduce hospitalizations from SNFs, study finds

Granting more authority to nurse practitioners is associated with reduced hospitalization of skilled nursing facility residents, according to recently published findings.

Pioneer ACO drops out of program, despite reductions in skilled nursing utilization

A California healthcare system has become the latest dropout from the Pioneer Accountable Care Organization program, despite reducing skilled nursing facility utilization and improving its readmission rates. Sharp HealthCare announced its decision in a quarterly financial statement released Tuesday.