High-tech wound dressing is shown to fight infection

Share this article:
High-tech wound dressing  is shown to fight infection
High-tech wound dressing is shown to fight infection
University of Wisconsin researchers have demonstrated how an ultra-thin layer of polymer impregnated with a surgical antibacterial can help healing by preventing infection.

Using a technology developed in the lab of Nicholas Abbott, a professor of chemical engineering, Abbott, Ankit Agarwal and colleagues crafted a polymer nanofilm containing chlorhexidine, and then stamped it onto a biologic wound dressing that is currently on the market.

The commercial dressing is sometimes called a skin substitute because it is embedded with biological compounds that promote healing, and so it is a prime treatment for burns and persistent wounds. But Agarwal, an honorary associate in the UW-Madison Department of Chemical Engineering, notes that infection can block healing in as many as 20% of patients.

To fight infection, physicians can place a gauze containing chlorhexidine on the biological dressing. But the high concentration of the anti-bacterial kills skin cells, slowing healing, and the gauze must be re-applied.

The nanotechnology approach releases a much smaller dose of chlorhexidine. This approach blocked infection while promoting healing.

In the first study to test specially treated nanofilms, the material reduced the number of bacteria colonies by 99.9% after three days, Agarwal said.

The goal was to reduce the antibacterial agent so that “it's not toxic to the healing cells, just to bacteria,” he said.
Full findings appear in the journal Biomaterials.
Share this article:

More in News

OIG: Nursing homes correctly reported 53% of abuse or neglect allegations in 2012

OIG: Nursing homes correctly reported 53% of abuse ...

Only about half of nursing facilities correctly reported abuse or neglect allegations in 2012, indicating that the government needs to provide more guidance and oversight, according to a new report ...

Aggressive blood pressure treatment does not increase fall risk after all, study ...

Taking aggressive measures to lower older adults' blood pressure may not increase their risk of falls, contrary to conventional wisdom, according to recently published research findings.

Hackers steal HIPAA-protected info of 4.5 million people from hospital network

Long-term care and other provider types already have been on the alert for large-scale computer breaches, and their concerns likely will be stoked by news that one of the nation's largest hospital organizations has been hacked. The personal information of about 4.5 million patients was ...