Experimental new Alzheimer's treatment could recover memory

Share this article:

The memories of Alzheimer's patients are forgotten but not gone, to twist a popular phrase. Now, one potential new treatment might help to recover some of those lost memories. An experimental drug has the potential to recover memory and improve cognitive function if taken early in Alzheimer's development–especially when coupled with other treatments, researchers say.

Scientists at the University of California Irvine have successfully recovered the memories of mice bred to develop age-related Alzheimer's symptoms by using an experimental drug that is being tested as a treatment for rheumatoid arthritis and psoriasis. The drug, identified as PMX205, prevents inflamed immune cells from accelerating neuron damage by congregating in areas of the brain with amyloid plaques, researchers said. Amyloid plaques are one of the most common physical brain characteristics found in Alzheimer's patients.

Over the course of a 12-week study, researchers tested the mice for cognitive ability and memory retention. Mice that received PMX205 during early stages of Alzheimer's performed nearly as well as normal mice on the tests, but mice receiving no treatment performed very poorly. When the brains of the mice were examined, researchers found up to 50% fewer Alzheimer's-related pathologies in the brains of the mice receiving PMX205 treatment. The report appears in the July 15 edition of The Journal of Immunology.

Share this article:

More in News

Long-term care continues to lead in deal volume and value: PwC report

Long-term care continues to lead in deal volume ...

Long-term care bucked healthcare industry trends with strong merger and acquisition activity in the second quarter of 2014, according to newly released data from professional services firm PricewaterhouseCoopers.

Empowering nurse practitioners could reduce hospitalizations from SNFs, study finds

Granting more authority to nurse practitioners is associated with reduced hospitalization of skilled nursing facility residents, according to recently published findings.

Pioneer ACO drops out of program, despite reductions in skilled nursing utilization

A California healthcare system has become the latest dropout from the Pioneer Accountable Care Organization program, despite reducing skilled nursing facility utilization and improving its readmission rates. Sharp HealthCare announced its decision in a quarterly financial statement released Tuesday.