Enzyme test could reveal who will need long-term care after one type of stroke, researchers say

Share this article:

By testing for particular molecules in cerebrospinal fluid, doctors can identify who is most likely to need long-term care following a subarachnoid haemorrhage (SAH) stroke, according to researchers.

A team of clinicians at Harvard University Medical School and researchers from Australia's Monash University discovered that SAH stroke patients with elevated levels of the enzyme endothelin converting enzyme-1 (ECE-1) and its substrate, big endothelin-1 (BigET-1), are likely to need long-term care.

"This is the first time doctors have had an early and accurate indication that disability will occur, giving them time to focus appropriate and aggressive therapies on this group of patients," stated researcher Sanjaya Kuruppu, Ph.D. "More importantly, it provides families with information required to make crucial decisions about subsequent long-term care."

Cerebrospinal fluid is already monitored post-stroke, meaning clinicians can test for these enzymes without putting the patient through any new procedures. The researchers say they are developing a rapid test for the enzyme and are planning a larger study.

Monash University released the results of the study Tuesday.

Share this article:

More in News

Also in the news for August 22, 2014

Iowa's nursing homes lost, on average, 41% of their employees each year from 2010-2012 ... Researchers identify proteins necessary in wound healing ... More than 40% percent of SSDI recipients take opioid pain relievers, study says.

CMS: Many skilled nursing providers have poor Medicare certification and recertification practices

CMS: Many skilled nursing providers have poor Medicare ...

The rate of improper Medicare payments to skilled nursing facilities has increased largely due to issues with certification and recertification statements, according to a recently released government memorandum. The Centers ...

NY nursing home agrees to $2.2 million settlement in case of false documentation

NY nursing home agrees to $2.2 million settlement ...

Nursing home operator Ralex Services Inc. has agreed to a $2.2 million settlement in a whistleblower case involving forged documents at a facility in New Rochelle, New York.