C. diff especially deadly for those with kidney disease, researchers find

Share this article:

People with end-stage renal disease (ESRD) have a significantly elevated risk of dying from Clostridium difficile infection, according to a recent study.

Researchers at Albert Einstein School of Medicine's Jacobi Medical Center in New York City compared outcomes of 104 ESRD patients on dialysis with a 300-person control group. They found those in the ESRD group had a C. diff-related mortality rate of 3.8%, while the other group's rate was 1.46%. ESRD patients were also more likely to have a relapse of severe C. diff infection within two months.

Combinining metronidazole and oral or rectal vancomycin was more effective than monotherapy drug treatment for the ESRD patients with C. diff, the researchers said. The monotherapy was associated with increased chances of a relapse, they found.

The research was released at the National Kidney Foundation 2013 Spring Clinical Meetings, held last week in Orlando, FL.

Share this article:

More in News

Skilled nursing facilities with poor quality ratings do not readmit more patients to hospitals, researchers find

Skilled nursing facilities with poor quality ratings do ...

Low-quality and high-quality skilled nursing facilities readmit about the same proportion of residents to hospitals, suggest research findings recently published in the American Journal of Medical Quality.

Cipro and related antibiotics increase MRSA risk in long-term care facilities, study ...

Long-term care residents on a fluoroquinolone antibiotic such as Cipro are at an increased risk for methicillin-resistant Staphylococcus aureus, researchers in France have found.

Jonathan Blum, who oversaw long-term care reforms, resigns as head of Medicare

The nation's top Medicare official, Jonathan Blum, is leaving his post next month, news outlets reported Tuesday. Blum became a familiar figure to long-term care providers through Open Door Forum calls and other outreach efforts during his five-year tenure, as he guided implementation of Medicare ...