Antipsychotics associated with weight gain, lower levels of good cholesterol in Alzheimer's patients

Share this article:
Two newer antipsychotic drugs have negative side effects in Alzheimer's patients. Both promote weight gain and one lowers levels of HDL "good" cholesterol, according to a new study.

The drugs associated with weight gain are olanzapine and quetiapine. Those who took olanzapine showed both weight gain and declines in HDL cholesterol. The study was to be published online April 15 in the American Journal of Psychiatry.

"These findings are especially troubling, because antipsychotics are associated with a higher risk of death and cerebrovascular adverse events in patients with dementia," according to principal investigator Dr. Lon S. Schneider in an American Psychiatric Association news release. "They're often used to minimize disruptive symptoms (such as psychosis or agitation), but patients should be monitored more closely."

Share this article:

More in News

CMS expands therapy payment research

The government is expanding its research into alternative therapy payments, to consider more holistic changes to the way Medicare reimburses skilled nursing facilities, the Centers for Medicare & Medicaid Services announced Tuesday.

CDC tightens Ebola guidelines for healthcare workers

The Centers for Disease Control and Prevention has issued more stringent guidelines for how healthcare workers should interact with Ebola patients, following an outcry from nurses and other professionals.

Nonprofit providers face alarming market forces, must rally, LeadingAge chairman says

Nonprofit providers face alarming market forces, must rally, ...

Nonprofit long-term care providers must work together to address alarming trends, or their market share could plummet and the sector as a whole could falter, LeadingAge Chairman David Gehm told ...