Researchers spot whose cognitive ability may shift during dementia trials
By
Kristen Fischer
Jan 17, 2024
People who changed cognitive status from impaired to normal during clinical trials tend to be younger, have better cognition and be negative for amyloid biomarkers, according to a new study.
Scientists identify protein linked to early-onset dementia
By
Kristen Fischer
Dec 13, 2023
Scientists have found a protein in the brain that’s linked to early-onset dementia and could also play a role in motor neuron disease.
Blood test spots which people with Alzheimer’s will benefit most from anti-amyloid drugs
By
Kristen Fischer
Dec 12, 2023
A blood test can tell which people may benefit most from anti-amyloid drugs — which could ease costs and prevent individuals from unneeded medicines, according to a new study published Dec. 4 in JAMA...
Changes in sleep patterns linked to poor cognitive function in older adults, study shows
By
Kristen Fischer
Dec 07, 2023
A new study sheds light on sleep and cognitive changes in older adults. Namely, sleeping for a short amount of time and sleep variability were linked to poor cognitive function, the authors reported.
Amyloid scans lower hospital visits — but not ED visits — in those with MCI, dementia
By
Kristen Fischer
Oct 11, 2023
A new study finds that using amyloid positron emission tomography scans can slightly reduce hospitalizations in people with mild cognitive impairment or dementia.
Better cardiovascular health may explain declining dementia rates: study
By
Alicia Lasek
Feb 27, 2023
U.S. dementia incidence has declined over recent decades. Yet the falling numbers haven’t been matched by a decrease in dementia-related brain pathology. Improved cardiovascular health may explain the...
FDA denies request for expedited approval of Alzheimer’s drug
By
John Roszkowski
Jan 23, 2023
The Food and Drug Administration late last week denied Ely Lilly’s request for expedited approval of the Alzheimer’s drug donanemab, citing the need for more clinical trials to test the safety and...
Race may impact accuracy of models predicting brain amyloidosis
Apr 25, 2022
Models using plasma Aβ42/Aβ40 to predict probability of CSF Aβ42/Aβ40 positivity not affected by race
Higher habitual coffee intake may slow cognitive decline
Nov 30, 2021
Higher baseline coffee consumption also linked to slower Aβ-amyloid accumulation during a 126-month study period as shown on brain MRI scans
A first: Researchers show inflammation is key driver of Alzheimer’s in living patients
By
Alicia Lasek
Aug 27, 2021
Treatments targeting inflammation could help reverse or at least slow the accumulation of pathologic tau protein in the brain — benefitting people with early dementia, investigators say.